Scientific studies confirm the potential of SANIST technology:

  • Cristoni et al. SANIST: optimization of a technology for compound identification based on the European Union directive with applications in forensic, pharmaceutical and food analyses. Journal of Mass Spectrometry. In press.
  • Albini et al. SANIST: a rapid mass spectrometric SACI/ESI data acquisition and elaboration platform for verifying potential candidate biomarkers. Rapid Commun Mass Spectrom. 2015 Oct 15;29(19):1703-10. Link

More than 40 scientific publications on international journals confirm the ISB know how and history in mass spectrometry field:


  • Cristoni S. et al. Development and applications of surface-activated chemical ionization.   Mass Spectrom Rev. 2007 Sep-Oct;26(5):645-56. Link


  • Martinez-Lozano Sinues P. et al. Secondary electrospray ionization-mass spectrometry and a novel statistical bioinformatic approach identifies a cancer-related profile in exhaled breath of breast cancer patients: a pilot study.J Breath Res. 2015 Sep 21;9(3):031001. doi: 10.1088/1752-7155/9/3/031001. Link
  • Cristoni S. et al. In-source cloud ion mobility mass spectrometry. Rapid Commun Mass Spectrom. 2015 Apr 15;29(7):690-4. Link
  • Cristoni S, Floridia M. PROSAD: a powerful platform for instrument calibration and quantification. Rapid Commun Mass Spectrom. 2014 Mar 15;28(5):536-44. Link
  • Rota C. et al. A serially coupled stationary phase method for the determination of urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine by liquid chromatography ion trap tandem mass spectrometry. Redox Biol. 2013 Oct 16;1:492-7. Link
  • Cristoni S,  Sinues PM et al. Mass spectrometry fingerprinting coupled to National Institute of Standards and Technology Mass Spectral search algorithm for pattern recognition. Anal Chim Acta. 2012 Nov 28;755:28-36. Link
  • Pedriali A, Cristoni S. et al. A redox proteomic investigation of oxidative stress caused by benzoylecgonine in the freshwater bivalve Dreissena polymorpha. Drug Test Anal. 2013 Aug;5(8):646-56. Link
  • Riva C, Cristoni S. et al. Effects of triclosan in the freshwater mussel Dreissena polymorpha: a proteomic investigation. Aquat Toxicol. 2012 Aug 15;118-119:62-71. Link
  • Cristoni S. et al. A system consisting of cation-exchange chromatography, combined surface-activated chemical and electrospray ionization, and ion-trap analysis for the analysis of 8-oxo-7,8-dihydro-2′-deoxyguanosine in urine. Rapid Commun Mass Spectrom. 2012 Feb 15;26(3):231-5. Link
  • Martínez-Lozano P., Cristoni S. et al. Secondary electrospray ionization-mass spectrometry: breath study on a control group. J Breath Res. 2011 Mar;5(1):016002. Link
  • Molin L, Cristoni S et al. Sieve-based device for MALDI sample preparation. III. Its power for quantitative measurements. J Mass Spectrom. 2011 Feb;46(2):230-6. Link
  • Cristoni S, Traldi P. et al. Sieve-based device for MALDI sample preparation. II. Instrumental parameterization. J Mass Spectrom. 2009 Nov;44(11):1579-86. Link
  • Traldi P, Cristoni S. et al. Sieve-based device for MALDI sample preparation. I. Influence of sample deposition conditions in oligonucleotide analysis to achieve significant increases in both sensitivity and resolution. J Mass Spectrom. 2008 Nov;43(11):1512-20. Link
  • Cristoni S. et al. Surface-activated chemical ionization and cation exchange chromatography for the analysis of enterotoxin A. J Mass Spectrom. 2009 Oct;44(10):1482-8. Link
  • Cristoni S. et al. MALDI-MS-NIST library approach for colorectal cancer diagnosis. Rapid Commun Mass Spectrom. 2009 Sep;23(17):2839-45. doi: 10.1002/rcm.4180. Link
  • Cristoni S. et al. On the coupling of ion-exchange chromatography to surface-activated chemical ionization in the analysis of highly polar metabolites in diluted urine samples. Rapid Commun Mass Spectrom. 2008 Jul;22(13):2134-8. Link
  • Lappolla A, Cristoni S. et al. Nonenzymatically glycated lipoprotein ApoA-I in plasma of diabetic and nephropathic patients. Ann N Y Acad Sci. 2008 Apr;1126:295-9. Link
  • Roncada P, Cristoni S. et al. Blood serum proteome for welfare evaluation in pigs. Vet Res Commun. 2007 Aug;31 Suppl 1:321-5. Link
  • Lapolla A, Cristoni S. On the search for glycated lipoprotein ApoA-I in the plasma of diabetic and nephropathic patients. J Mass Spectrom. 2008 Jan;43(1):74-81. Link
  • Cristoni S. et al. Surface-activated chemical ionization ion trap mass spectrometry for the analysis of cocaine and benzoylecgonine in hair after extraction and sample dilution. Rapid Commun Mass Spectrom. 2007;21(15):2515-23. Link
  • Iafelice R, Cristoni S. et al. Identification of the sites of deoxyhaemoglobin PEGylation. Biochem J. 2007 Apr 1;403(1):189-96. Link
  • Cristoni S. et al. Analysis of rosuvatatin by imaging mass spectrometry. Rapid Commun Mass Spectrom. 2006;20(22):3483-7. Link