Mass spectrometry


The general mass spectrometry principles and applications

Mass spectrometry is a technology used to detect analyte on the basis of their specific mass/charge (m/z) ratio. Basically, its technological core is composed by two main section.

  • Analyte ionization: in this section the analytes are ionized by means of different chemical physical approaches (e.g: under and electron flow placed in high field conditions (70 ev), using high voltages (3000 – 6000 V) to ionize liquids analyte, using laser to ionize solid compounds).
  • Mass spectrometry analyzer: after ionization the charged analyte motio can be manipulated appling electromagnetic frequencies in a high vacum region (pressure < 10-4 Torr). Using the different kind of correlationg among the instrument applied frequency and the ion ones it is so possible