Metabolomics, proteomics and genomics could be integrated with genomics an bioinformatics so to obtain a systemic approach for disease diagnosis and treatment. This strategy is particular important in the case of rare diseases. In these pathologies the technologies can lead to obtain the follow informations:
- Gene expression potentially associated with the disease;
- Epigenetic disease correlation;
- Proteomics expression correlation;
- Metabolomics expression correlation.
These informations make possible to find the potential disease cause (e.g.: intestinal disbiosis) and to associate it to the enzymatic funtional disfunction. The knowledge of these data provide useful indications to be used for personalized and precision medicine therapy.