Metabolomics proteomics genomics and bioinformatics in rare disease diagnosis and therapy

Metabolomics, proteomics and genomics could be integrated with genomics an bioinformatics so to obtain a systemic approach for disease diagnosis and treatment.  This strategy is particular important in the case of rare diseases. In these pathologies the technologies can lead to obtain the follow informations:

  • Gene expression potentially associated with the disease;
  • Epigenetic disease correlation;
  • Proteomics expression correlation;
  • Metabolomics expression correlation.

These informations make possible to  find the potential disease cause (e.g.: intestinal disbiosis) and to associate it to the enzymatic funtional disfunction. The knowledge of these data provide useful indications to be used for personalized and precision medicine therapy.

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